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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6190 | Telaprevir | VX-950,LY-570310,Incivek,MP-424 | HCV Protease , SARS-CoV |
Telaprevir (Incivek) (VX-950) is an effective inhibitor of HCV NS3-4A serine protease (IC50: 0.35 μM). | |||
T60085 | MM3122 | GTPL11533,MM-3122,Ac-GQFR-kbt | SARS-CoV |
MM3122 (MM-3122) is a selective type II transmembrane serine protease (TMPRSS2) inhibitor, IC50 = 0.34 nM. MM3122 effectively blocks TMPRSS2, thereby inhibiting the entry of SARS-CoV-2 and MERS-CoV into human cells. | |||
TP1792L | KKI-5 acetate(97145-43-2 free base) | Serine Protease | |
KKI-5 acetate is a serine protease inhibitor that inhibits kallikrein and plasmin. KKI 5 may exhibit anticancer chemotherapeutic benefit and may also be used as a treatment for angioedema. | |||
T2392 | Nafamostat mesylate | FUT-175 | Apoptosis , Serine/threonin kinase , SARS-CoV , Serine Protease |
Nafamostat mesylate (FUT-175), a synthetic serine protease inhibitor, has been used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic dermatitis. | |||
T76870 | Narsoplimab | OMS 721 | SARS-CoV |
Narsoplimab (OMS 721) is a selective whole-human immunoglobulin gamma-4 (IgG4) monoclonal antibody, a mannan-binding lectin-associated serine protease-2 (MASP-2) inhibitor that binds MASP-2 and prevents lectin pathway ac... | |||
T76157 | Chymotrypsinogen | ||
Chymotrypsinogen is an inactive precursor of Chymotrypsin . Chymotrypsin is a serine protease produced by the pancreas [1] [2] . | |||
T69035 | Camostat free base | ||
Camostat, also known as FOY 305, is a serine protease inhibitor. Camostat is used in the treatment of some forms of cancer and is also effective against some viral infections, as well as inhibiting fibrosis in liver or... | |||
T76489 | Fluorescent Substrate for Subtillsin | ||
Subtilisin, a bacterial serine protease [1] [2], can be detected through the activity of a fluorescent substrate designed specifically for subtilisin. | |||
T78354 | Subtilisin | EC 3.4.21.14 | |
Subtilisin, also known as rubinase, is a serine protease of bacterial origin. This enzyme exhibits thermal stability, pH tolerance, and calcium-dependent stability, characteristics that make it suitable for use as an add... | |||
T38052 | CRA-2059 TFA | ||
CRA-2059 is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2]. Tryptase is a trypsin-like serine protease found as a major protein component in human ma... | |||
T38051 | CRA-2059 hydrochloride | ||
CRA-2059 hydrochloride is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2]. Tryptase is a trypsin-like serine protease found as a major protein compone... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01580 | PRSS2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Trypsin-2, also known as Trypsin II, Anionic trypsinogen, Serine protease 2, PRSS2 and TRY2, is a secreted protein that belongs to the trypsin serine protease family including Trypsin, PRSS1, PRSS2 and PRSS3. It consists... | |||
TMPY-02117 | Marapsin Protein, Human, Recombinant (His) | Human | HEK293 |
The name "Pancreasin" because it is transcribed strongly in the pancreas. This secreted, tryptic serine protease, also known as Marapsin or PRSS27 (Protease, serine, 27), is a member of the peptidase S1 family. Pancreasi... | |||
TMPH-03244 | Anionic trypsin-2 Protein, Rat, Recombinant (His) | Rat | Yeast |
Anionic trypsin-2 Protein, Rat, Recombinant (His) is expressed in Yeast. | |||
TMPJ-01032 | SPINK7 Protein, Human, Recombinant (His) | Human | Human Cells |
Serine protease inhibitor Kazal-type 7(SPINK7) is a secreted protein, that in humans is encoded by the SPINK7 gene. SPINK7 contains 1 Kazal-like domain. SPINK7 is probably serine protease inhibitor. Recombinant human SPI... | |||
TMPH-01773 | ELANE Protein, Human, Recombinant (GST) | Human | E. coli |
Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis. Capable of killing E.coli but not S.aureus in vitro; digests outer membrane pro... | |||
TMPY-02078 | HtrA2/Omi Protein, Human, Recombinant (His) | Human | E. coli |
Serine protease HTRA2, also known as high-temperature requirement protein A2, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI and HTRA2, is a single-pass membrane protein that belongs to the ... | |||
TMPJ-01204 | TPSAB1 Protein, Human, Recombinant (His) | Human | Human Cells |
Tryptases are serine proteases with trypsin-like specificity. Together with chymases and Cathepsin G, tryptases are important players in mast cell mediation of inflammatory and allergic responses. Tryptase alpha/beta-1(T... | |||
TMPY-00915 | Serpin A1 Protein, Human, Recombinant (His) | Human | HEK293 |
SerpinA1, also known as Alpha-1 antitrypsin (AAT), is a prototype member of the Serpin superfamily of the serine protease inhibitors. This serine protease inhibitor blocks the protease, neutrophil elastase. Alpha-1 antit... | |||
TMPY-05094 | Tissue Factor Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemost... | |||
TMPY-02530 | Tissue Factor Protein, Human, Recombinant (His) | Human | HEK293 |
Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemost... | |||
TMPY-00904 | Urokinase/uPA Protein, Human, Recombinant (His) | Human | HEK293 |
Plasminogen activator, urokinase, also known as PLAU and uPA, is a serine protease which converts plasminogen to plasmin, a broad-spectrum protease active on extracellular matrix (ECM) components. It is involved in compl... | |||
TMPY-02767 | TPP1 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Tripeptidyl-peptidase 1 (TPP1 / CLN2) is a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activit... | |||
TMPY-02141 | UPAR/PLAUR Protein, Human, Recombinant (His) | Human | HEK293 |
Urokinase plasminogen activator (uPA) and/or its receptor (uPAR) are essential for metastasis, and overexpression of these molecules is strongly correlated with poor prognosis in a variety of malignant tumours. uPAR and ... | |||
TMPY-01257 | UPAR/PLAUR Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Urokinase plasminogen activator (uPA) and/or its receptor (uPAR) are essential for metastasis, and overexpression of these molecules is strongly correlated with poor prognosis in a variety of malignant tumours. uPAR and ... | |||
TMPY-04815 | C1 inhibitor Protein, Rat, Recombinant (His) | Rat | HEK293 |
Plasma protease C1 inhibitor, also known as C1-inhibiting factor, C1-INH, C1 esterase inhibitor, SERPING1 and C1IN, is a serine proteinase inhibitor (serpin) that regulates activation of both the complement and contact s... | |||
TMPY-00926 | HAI-2/SPINT2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Choanal (CA) and gastrointestinal atresias (GA) are an important feature of syndromic congenital sodium diarrhea (sCSD), a disorder recently associated with mutations in the gene for serine protease inhibitor type 2 (SPI... | |||
TMPH-02607 | Complement factor B Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convert... | |||
TMPY-01900 | Kallikrein 4/KLK4 Protein, Human, Recombinant (His) | Human | HEK293 |
Kallikrein-4, also known as Enamel matrix serine proteinase 1, Kallikrein-like protein 1, KLK-L1, Serine protease 17, KLK4, PRSS17, and EMSP1, is a secreted protein that belongs to the peptidase S1 family and Kallikrein ... | |||
TMPK-00581 | MASP2 Protein, Rat, Recombinant (E. coli, His) | Rat | E. coli |
The dysregulation of complement cascade leads to unsolicited cytokine storm, inflammation, deterioration of alveolar lining cells, culminating in acquired respiratory destructive syndrome (ARDS). Similar pathogenesis is ... | |||
TMPH-02342 | Collagenase Protein, Hypoderma lineatum, Recombinant (His & Myc) | Hypoderma lineatum | E. coli |
This enzyme is a serine protease capable of degrading the native triple helix of collagen. Also cleaves the B chain of insulin at the 15-Leu-|-Try-16 and 22-Arg-|-Gly-23 bonds. Hydrolyzes casein, but not Px-Pro-Leu-Gly-P... | |||
TMPK-00705 | MASP2 Protein, Human, Recombinant (His) | Human | E. coli |
The pathogenesis of severe acute respiratory disease syndrome (SARS) is not fully understood. One case-control study has reported an association between susceptibility to SARS and mannan-binding lectin (MBL) in China. As... | |||
TMPK-00582 | MASP2 Protein (Primary Amine Labeling), Rat, Recombinant (His), Biotinylated | Rat | E. coli |
The dysregulation of complement cascade leads to unsolicited cytokine storm, inflammation, deterioration of alveolar lining cells, culminating in acquired respiratory destructive syndrome (ARDS). Similar pathogenesis is ... | |||
TMPK-00496 | MASP2 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | E. coli |
The dysregulation of complement cascade leads to unsolicited cytokine storm, inflammation, deterioration of alveolar lining cells, culminating in acquired respiratory destructive syndrome (ARDS). Similar pathogenesis is ... | |||
TMPJ-00929 | Serpin B3 Protein, Human, Recombinant (N-His) | Human | E. coli |
Serpin B3, also known as squamous cell carcinoma antigen-1 (SCCA-1), is a member of the serpin superfamily of serine protease inhibitors. Serpin B3 belongs to the subgroup ovalbumin-related serpins which are involved in ... | |||
TMPK-01126 | MASP2 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
The dysregulation of complement cascade leads to unsolicited cytokine storm, inflammation, deterioration of alveolar lining cells, culminating in acquired respiratory destructive syndrome (ARDS). Similar pathogenesis is ... | |||
TMPH-02239 | TMPRSS4 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Plasma membrane-anchored serine protease that directly induces processing of pro-uPA/PLAU into the active form through proteolytic activity. Seems to be capable of activating ENaC.; (Microbial infection) In gut epithelia... | |||
TMPJ-00928 | Serpin B3 Protein, Human, Recombinant (C-His) | Human | Human Cells |
Serpin B3, also known as squamous cell carcinoma antigen-1 (SCCA-1), is a member of the serpin superfamily of serine protease inhibitors. Serpin B3 belongs to the subgroup ovalbumin-related serpins which are involved in ... | |||
TMPY-02786 | Kallikrein 11/KLK11 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
kallikrein-related peptidase 11 (KLK11), also known as hippostasin, trypsin-like serine protease, and PRSS2, is a member of the human tissue kallikrein family. It is a subgroup of serine proteases with diverse physiologi... | |||
TMPY-01105 | Kallikrein 11/KLK11 Protein, Human, Recombinant (His) | Human | HEK293 |
kallikrein-related peptidase 11 (KLK11), also known as hippostasin, trypsin-like serine protease, and PRSS2, is a member of the human tissue kallikrein family. It is a subgroup of serine proteases with diverse physiologi... | |||
TMPY-04230 | HAI-2/SPINT2 Protein, Human, Recombinant (His) | Human | HEK293 |
Choanal (CA) and gastrointestinal atresias (GA) are an important feature of syndromic congenital sodium diarrhea (sCSD), a disorder recently associated with mutations in the gene for serine protease inhibitor type 2 (SPI... | |||
TMPY-00474 | HAI-2/SPINT2 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Choanal (CA) and gastrointestinal atresias (GA) are an important feature of syndromic congenital sodium diarrhea (sCSD), a disorder recently associated with mutations in the gene for serine protease inhibitor type 2 (SPI... | |||
TMPY-01909 | Elafin Protein, Human, Recombinant (His) | Human | HEK293 |
Elafin, also known as Elastase-specific inhibitor, Peptidase inhibitor 3, Protease inhibitor WAP3, Skin-derived antileukoproteinase, WAP four-disulfide core domain protein 14, PI3, WAP3 and WFDC14, is a secreted protein ... | |||
TMPH-02833 | PAI-1 Protein, Mouse, Recombinant (His) | Mouse | Yeast |
Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-reg... | |||
TMPH-02834 | PAI-1 Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-reg... | |||
TMPJ-00302 | Serpin F2 Protein, Mouse, Recombinant (hFc) | Mouse | Human Cells |
Alpha-2-antiplasmin, also called Serpin F2, is a serine protease inhibitor (serpin) responsible for inactivating plasmin, and an important enzyme participates in fibrinolysis and degradation of other proteins. In liver c... | |||
TMPY-01814 | GASP-1/WFIKKN2 Protein, Human, Recombinant (His) | Human | HEK293 |
WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 2, also known as Growth and differentiation factor-associated serum protein 1, WAP, follistatin, immunoglobulin, kunitz and NTR domain-containing-relat... | |||
TMPJ-00891 | Kallikrein 2/KLK2 Protein, Human, Recombinant (His) | Human | Human Cells |
Kallikrein-2 (KLK2) is a secreted serine protease that belongs to the peptidase S1 family of Kallikrein subfamily. KLK2 contains 1 peptidase S1 domain. It is highly expressed in the human prostate gland. KLK2 can cleave ... | |||
TMPH-02237 | TMPRSS2 Protein, Human, Recombinant (His & Myc) | Human | HEK293 |
Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-... | |||
TMPH-02235 | TMPRSS2 Protein, Human, Recombinant (Cell-Free, His) | Human | in vitro E. coli expression system |
Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-... | |||
TMPH-02238 | TMPRSS2 Protein, Human, Recombinant (Avi & His & MBP), Biotinylated | Human | E. coli |
Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-... | |||
TMPH-02236 | TMPRSS2 Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-... | |||
TMPY-05083 | Tissue Factor Protein, Human, Recombinant (aa 1-295, His) | Human | Baculovirus-Insect Cells |
Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemost... | |||
TMPY-03209 | Tissue Factor Protein, Rat, Recombinant (His) | Rat | HEK293 |
Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemost... | |||
TMPY-02318 | Tissue Factor Protein, Rabbit, Recombinant (His) | Rabbit | HEK293 |
Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemost... | |||
TMPY-01325 | Tissue Factor Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemost... | |||
TMPY-00442 | Serpin A1 Protein, Rat, Recombinant (His) | Rat | HEK293 |
SerpinA1, also known as Alpha-1 antitrypsin (AAT), is a prototype member of the Serpin superfamily of the serine protease inhibitors. This serine protease inhibitor blocks the protease, neutrophil elastase. Alpha-1 antit... | |||
TMPY-06957 | Tissue Factor Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | HEK293 |
Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemost... | |||
TMPY-02537 | Tissue Factor Protein, Human, Recombinant (hFc) | Human | HEK293 |
Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemost... | |||
TMPY-01026 | Alpha 2 Antiplasmin/SerpinF2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
SerpinF2, also known as alpha-2 antiplasmin (alpha-2 AP), is a member of the Serpin superfamily. SerpinF2 is the principal physiological inhibitor of serine protease plasmin, and as well as, an efficient inhibitor of try... | |||
TMPY-01398 | Alpha 2 Antiplasmin/SerpinF2 Protein, Human, Recombinant (His) | Human | HEK293 |
SerpinF2, also known as alpha-2 antiplasmin (alpha-2 AP), is a member of the Serpin superfamily. SerpinF2 is the principal physiological inhibitor of serine protease plasmin, and as well as, an efficient inhibitor of try... | |||
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